Excimer laser versus narrow-band UVB (311 nm) in the treatment of psoriasis vulgaris.

Type:Uv phototherapy Time:2015-01-07 17:04:39

The excimer laser is a new therapeutic option in the treatment of psoriasis vulgaris.

OBJECTIVE:

The purpose of this study was to determine the response of psoriasis lesions to the 308-nm excimer laser compared to 311-nm UVB phototherapy.

METHODS:

In this prospective right/left comparative, open, single-blinded trial, selected psoriasis plaques of 16 patients were treated with the excimer laser whereas the rest of the body was treated with UVB narrow-band phototherapy. A modified PASI score was used to evaluate the results.

RESULTS:

After 12 treatments, 15 patients were evaluated. In 2 patients no difference between the two body sides was observed.

In 9 patients the laser-treated lesions showed better results, whereas in 4 patients the side treated with 311-nm UVB showed more clearing. The mean reduction in PASI score was 5.6 and 4.9, respectively (difference not significant).

CONCLUSION:

The use of the 308-nm xenon chloride excimer laser is an additional effective therapeutic option for the treatment of psoriasis vulgaris.

Goldinger SM1, Dummer R, Schmid P, Prinz Vavricka M, Burg G, Lauchli S

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