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Langerhans cell histiocytosis treated with narrow-band ultraviolet B
Type:Uv phototherapy Time:2014-12-12 15:29:59Langerhans cell histiocytosis treated with narrow-band ultraviolet B.
Aihara M1, Hasegawa T, Okuyama Y, Hiruma M, Ikeda S.
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Abstract
A 58-year-old man had widespread multiple erythemas that had been untreated for 20 years. The cutaneous lesions increased in
size for a year. Histopathological examination revealed increased number of large, dysplastic, histiocytic cells in the
dermis; most of these cells tested positive for Langelin, CD1a and S-100 staining. The patient was diagnosed with Langerhans
cell histiocytosis (LCH) and treated with narrow-band ultraviolet B (NB-UVB) radiation. The erythema improved after
treatment, but the tumor remained. Therefore, the tumor was surgically excised. NB-UVB therapy might be effective for the
treatment of superficial lesions, but not tumoral lesions of LCH.
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