Narrowband UVB treatment of progressive macular hypomelanosis

Type:Uv phototherapy   Time:2014-12-08 12:00:36
Narrowband UVB treatment of progressive macular hypomelanosis.
Kim MB1, Kim GW, Cho HH, Park HJ, Kim HS, Kim SH, Kim BS, Ko HC.
Author information
Abstract
BACKGROUND:
Little information is available on effective treatments for progressive macular hypomelanosis (PMH). To our knowledge, only 

one case of narrowband ultraviolet B (NB-UVB) therapy as an efficient treatment for patients with PMH has been reported in 

the recent literature.
OBJECTIVE:
We aimed to investigate the clinical features of PMH in Koreans and to determine the therapeutic efficacy of NB-UVB therapy 

in the management of PMH.
METHODS:
We performed an uncontrolled prospective study designed to evaluate the usefulness of NB-UVB therapy in PMH. A total of 23 

patients with PMH were enrolled in the study. Of these, 17 patients underwent treatment with NB-UVB therapy once or twice 

weekly and were eligible for analysis. The remaining 6 patients were lost to follow-up before completion of the treatment. 

Repigmentation was evaluated by two dermatologists using photographic documentation.
RESULTS:
In our trial, NB-UVB therapy was used successfully in 9 of 16 patients (56.2%), who showed more than 90% repigmentation. We 

found that 13 of 16 patients (81.3%) experienced at least 50% repigmentation. The repigmented sites showed an excellent color 

match. No signs of recurrence have been detected in 11 of these 16 patients (68.7%) up to the present time (13.2 ¡À 8.2 

months of follow-up).
LIMITATIONS:
Our study includes a small number of subjects examined, and it was an uncontrolled and non-double-blind study.
CONCLUSIONS:
The findings of this study suggest that NB-UVB therapy is an effective and safe method for use in the treatment of PMH.
www.kerneluvb.com----The leader manufacturer of UV Phototherapy.