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A case of recurrent impetigo herpetiformis treated with systemic corticosteroids and narrowband UVB.

Bozdag K1, Ozturk S, Ermete M.

Author information

Abstract

Impetigo herpetiformis is a rare pustular eruption with usual onset during the third trimester of pregnancy. The disease 

tends to remit after delivery, but may recur in subsequent pregnancies. Here we present a recurrent case of impetigo 

herpetiformis with earlier onset and poor response to corticosteroids in the subsequent pregnancy. She had widespread, 

erythematosquamous patches with tiny superficial pustules in the third trimester of her first pregnancy. Histopathological 

and clinical findings were consistent with impetigo herpetiformis. She was treated with systemic prednisolone and had a 

healthy baby without any complication. Three years later, the patient presented with impetigo herpetiformis again in the 

second trimester of her second pregnancy. After six weeks of oral prednisolone treatment, the lesions improved, but there 

were still new pustule formations and narrowband ultraviolet B treatment was added. Skin eruption cleared and she had a 

healthy baby in the 38th week of her second pregnancy. The corticosteroid dose was tapered gradually and stopped after 

delivery. Early diagnosis and treatment is crucial in impetigo herpetiformis because of the risk of maternal and fetal 

complications. When prednisolone is not enough to control the eruption alone, narrowband UVB can safely be added to the 

treatment.

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