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Psoralen plus ultraviolet A (PUVA) soaks and UVB TL01 treatment for chronic hand dermatoses.

Jensen L, Stensgaard A, Andersen KE.

Author information

Abstract

Chronic eczematous hand dermatoses with and without contact allergies are complex diseases, which makes it a challenge to 

select the best treatment and obtain an optimal patient experience and a satisfactory treatment result. The aim of this study 

was to evaluate retrospectively the clinical effect and patient experience of local treatment with psoralen plus ultraviolet 

A (PUVA) soaks and TL01 phototherapy for severe chronic hand dermatoses, and also to evaluate the quality of life for the 

subgroup of patients with allergic contact dermatitis including Compositae allergy. A retrospective evaluation of results for 

94 consecutive patients having received a total of 121 treatment courses with local PUVA soaks or TL01 phototherapy for one 

of the following diagnoses (n=number of treatment courses): psoriasis (n=19), hyperk-eratotic hand eczema (n=27), Pustulosis 

Palmoplantaris (PPP) (n=22), vesicular eczema (n=16), Compositae dermatitis (n=24), and allergic contact dermatitis (n=13). 

Moreover, semi-structured interviews with 6 selected patients having multiple contact allergies including Compositae allergy 

were used to evaluate quality of life. As a result, we found that PUVA soaks has good effect in patients with psoriasis and 

hyperkeratotic hand eczema and local phototherapy for chronic hand dermatoses is a useful treatment option in selected cases.

KEYWORDS:

PUVA soaks; compositae allergy.; hand eczema; quality of life

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