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Ultraviolet light is a general term for wavelengths from 200 nm to 400 nm in the electromagnetic spectrum. It is classified according to wavelength: short-wave ultraviolet (UVC, wavelength between 200 and 280 nm), medium-wave ultraviolet (UVB, wavelength between 280 and 320 nm), and long-wave ultraviolet (UVA, wavelength between 320 and 400 nm).

    The depth of UV light that penetrates human skin is closely related to wavelength. Most of the short-wave ultraviolet rays are reflected and absorbed by the stratum corneum of the skin, and only a small part penetrates into the spine cell layer. Most of the UVB is absorbed by the skin epidermis, and a small part can reach the dermal papilla layer. A small part of the long-wave ultraviolet light is absorbed by the epidermis, and most of it can penetrate into the dermis, and the deepest reaches the middle of the dermis.

    Ultraviolet light can be used to treat skin diseases, and the choice of wavelength is important for the treatment of skin diseases. The most widely used clinically is UVB, which is the most active part of UV biological activity. Ultraviolet rays cause a variety of biological effects after being absorbed by the skin. There are:

    (1) Forming vitamin D. Ultraviolet rays act on 7-deoxycholesterol on the skin to form vitamin D3.

    (2) promote the formation of melanin in the skin. Under the action of ultraviolet rays, the melanocyte volume per unit area of ​​the epidermis increases, the activity of tyrosinase is enhanced, and the synthesized melanin is increased, thereby darkening the skin.

    (3) Enhance the barrier function of the skin. Ultraviolet radiation can thicken the stratum corneum of the skin, strengthen the skin's resistance to external damage, and reduce the penetration of pathogens, antigens and various harmful substances into the body.

    (4) affecting immune function. Mainly reflected in two aspects: 1 inhibition of immune response. Ultraviolet radiation can inhibit allergic reactions to local skin contact, and the allergic reaction caused by contact with allergens is weakened or even prevented. 2 induce the release of immunologically active substances. Ultraviolet irradiation can cause keratinocytes to form various interleukins and tumor necrosis factor-�� and participate in the activation, differentiation and reproduction of immune cells, and play a role in regulating inflammatory reactions and allergic reactions.

    (5) causing skin erythema reaction.

    According to a variety of biological effects caused by UV absorption by the skin, it can treat a variety of skin diseases such as: psoriasis, vitiligo, atopic dermatitis, eczema, urticaria, alopecia areata, frostbite, herpes zoster, folliculitis, roses Pityriasis, parapsoriasis, seborrheic dermatitis, neurodermatitis, tinea versicolor, chronic skin ulcers, generalized lichen planus, mycosis fungoides, palmoplantar pustulosis, contact dermatitis, lichen-like pityriasis Wait.

    The study found that mid-wave ultraviolet rays around 310 nm have the best therapeutic effect on skin diseases, low incidence of adverse reactions, and long time for disease remission. The dermatology department of our hospital adopts Waldmann photoelectric therapy equipment imported from Germany and emits narrow-spectrum UVB with wavelength of 311 ~ 312nm, which is the highest level of ultraviolet light wave treatment in the world today. It has been clinically proven by many large medical units at home and abroad: it is stable, safe and reliable, and it has received good treatment evaluation all over the world. By the end of 2009, our department of UV phototherapy more than 12,000 people, have achieved good clinical results.