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Various treatment methods for vitiligo take a long time to produce curative effect, and the treatment process should not be rushed, and patient medication should be adhered to. At present, with the continuous development of medical technology, some auxiliary medical devices are continuously applied to the treatment of various diseases, and ultraviolet phototherapy is one of them. So, what is the principle of ultraviolet phototherapy for vitiligo?

For patients with vitiligo, the occurrence of any disease and the patient's own immunity is completely inseparable. Patients in life can exercise moderately to enhance their immunity, thereby promoting blood circulation and stimulating the regeneration of melanocytes. Stay optimistic and treat the disease. Because vitiligo is more harmful to the patient's appearance, it is difficult for patients to accept such facts. It is inevitable that they will be uneasy. At this time, the most important thing for patients is to be calm and optimistic to face the disease.

The indications for UV phototherapy include: psoriasis vulgaris, vitiligo, chronic eczema, neurodermatitis, atopic dermatitis, palmoplantar pustulosis, pityriasis rosea, alopecia areata, parapsoriasis, chronic ulcers, Mycosis fungoides, various light diseases. NB-UVB is the world's skin phototherapy method. It uses a narrow-spectrum medium-wave ultraviolet light with a peak value of 311 nm. It concentrates the most biologically active part of the ultraviolet light directly on the affected area of ​​the skin, and filters out the harmful ultraviolet rays harmful to the skin. The side effect is small, and it acts on the stratum corneum of the skin, and the onset time is short, and the effect is quick. It is the most commonly used method for treating vitiligo in foreign countries.

The biological mechanism of NB-UVB treatment of vitiligo has the following aspects: 1. Stimulate the proliferation and migration of melanocytes. When melanocytes absorb UVB energy, they can stimulate the activity of tyrosinase and accelerate tyrosine. Oxidation and polymerization, increase melanin synthesis; 2, can promote keratinocytes release melanocyte proliferation and differentiation factors such as endothelin-1, fibroblast growth factor, etc.; 3, UVB has immunosuppressive effect, can make migration And proliferating melanocytes are protected from damage.