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1) Psoriasis:

Narrowband UVB (narrowband UVB) for the treatment of psoriasis (311 ~ 312nm UVB):

The study found that <295nm UVB has no anti-psoriatic effect, but it causes obvious erythema reaction. The UVB of 300-313 nm has the best anti-psoriatic activity, which can alleviate psoriasis. Clinical practice shows that the efficacy of 311nm UVB is better than that of broad-spectrum UVB, the incidence of erythema reaction is low, the disease is relieved for a long time, the effect is similar to PUVA, but it does not need to take medicine, the cost is low, it can be used for pregnant women and children, and the carcinogenicity is small. The minimum phototoxicity was determined before treatment, and the amount of matt toxic was used as the initial irradiation amount. Irradiate once every other day, 15-20 times for a course of treatment. Europe is widely used, and US applications are gradually increasing.

2) Vitiligo:

Vitiligo is a pigmentation loss spot caused by a decrease or loss of skin melanocytes. Using photochemotherapy (8-oxy-psoralen plus UVA light) or narrow-spectrum UVB (311 nm) irradiation, it activates tyrosinase activity and promotes melanin formation. The minimum phototoxicity was measured before treatment, and the amount of matt toxic was used as the initial exposure, 2-3 times per week. Need to adhere to treatment, usually need 30-50 times or more treatment.

3) Rose pityriasis:

Pityriasis rosea is a common self-limiting inflammatory skin disease. The onset may be related to viral infection, using physical therapy that is ultraviolet (UVA or narrow-spectrum UVB) irradiation, irradiation with sub-erythroid dose, once every other day, 10 times for a course of treatment.

(4) refractory atopic dermatitis:

The treatment was performed with narrow-spectrum UVB TL01 (311 nm) light, and the dose of sub-erythema was used as the initial dose, which was increased by about 20% each time until the light red spot appeared, and the dose was maintained three times a week, 15-25 times for one course of treatment.

(5) severe seborrheic dermatitis:

Seborrheic dermatitis is a very common papular scaly skin disease, and the incidence rate is 2 to 10% of the adult population. The treatment is limited and the curative effect is not good. Treatment with narrow-spectrum UVB TL01 (311 nm) light, the amount of sub-erythroid dose is the initial dose, each increase of about 20%, until the occurrence of light red spots to maintain the dose, three times a week, 8 weeks for a course of treatment.

(6) Parapsoriasis:

Parapsoriasis, a group of chronic skin diseases of unknown etiology, characterized by erythema, papules, infiltration, and scales without symptoms. Alternate irradiation with photochemotherapy (PUVA) or UVB irradiation or UVB and UVA can be used. Apply a mild lubricant to the outside before irradiation. 10-20 times for a course of treatment.

(7) MF and palmoplantar pustulosis:

MF and palmoplantar pustulosis have a long course of disease, self-limiting, no special drugs to treat, the use of phototherapy treatment is good, can reduce or not use immunosuppressants. Palmoplantar pustulosis is effective 4 to 5 times. MF works quickly, but it takes a long time to consolidate.

(8) Other:

 

Photochemotherapy (PUVA), narrow-spectrum UVB irradiation or UVA and UVB mixed irradiation, also have a good effect on atopic dermatitis, eczema, herpes zoster, postherpetic neuralgia

The traditional NB-UVB ultraviolet phototherapy apparatus on the market mostly uses NB-UVB narrow-wave phototherapy lamps (special phosphors in the lamps can generate a large amount of UV-B-band ultraviolet rays), and the illumination light generated by the lamps is absorbed by the endogenous color base. The series of extreme reactions of these biomolecules lead to photobiochemical changes in the skin, which ultimately lead to therapeutic effects.