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Narrow-spectrum UVB definition

NB-UVB refers to a specific ultraviolet band having a wavelength of 311 to 312 nm and a peak of 311 nm. It has the functions of inhibiting cell proliferation, immune function, vitamin D synthesis, etc., and has been used in the treatment of various skin diseases. It is one of the main methods for treating psoriasis in recent years. It can directly induce T cell apoptosis, inhibit the number and function of epidermal Langerhans cells, and reduce the activity of NK cells for therapeutic purposes. Therefore, the effect is fast, the effect is equal to or better than PUVA, and the side effects are low, which has been accepted by medical workers and patients.

Advantages of narrow-band UVB in the treatment of skin diseases

At the end of the last century, scientists separated the ultraviolet bands from the beginning of this century and found that the specific ultraviolet wavelength of 311 nm narrow-band UVB has a significant effect in clinical application, especially in the treatment of psoriasis and vitiligo. Cleaning and recovery time is superior to traditional light therapy and is the most therapeutic ingredient. Compared with traditional PUVA therapy, narrow-band UVB has the following advantages: 1. It has good curative effect on common plaque psoriasis, 2. The method is simple, and the incidence of adverse reactions is low. 3. Each irradiation time is short and does not exceed 7 Minutes, 3, only need to wear UV protective glasses during the irradiation treatment.

Indications for narrow-band UVB:

1, mainly: psoriasis, vitiligo, rose pityriasis;

2, followed by: atopic dermatitis, seborrheic dermatitis, mycosis fungoides, folliculitis, eczema, herpes zoster and so on.

Contraindications for narrow-band UVB treatment:

Family history of melanoma; severe photodamage; low immunity; active tuberculosis; hyperthyroidism; heart and kidney dysfunction; skin tumor; cataract; lens removal; photosensitive skin disease; receiving isotope or radiotherapy; less than 12 years old.

Photosensitive drugs such as tetracycline, griseofulvin, quinolones, sulfonamides, promethazine, hibernation and some photosensitizing foods should not be taken before receiving narrow-spectrum UVB treatment.

Adverse reactions of narrow-band UVB:

NB-UVB irradiation treatment time is relatively short, no photosensitizer caused by nausea, dizziness, phototoxic reaction, etc., no need for eye protection after treatment; no long-term skin tumor has not been found. The main adverse reactions and their prevention and control measures are as follows:

1. Dry skin itching: moisturizing cream or fat;

2. Excessive erythema reaction: - control dose, distance, irradiation field;

3. Skin photoaging: no long-term phototherapy, sunscreen;

4. Pigmentation: pigmentation can be restored;

5. Cataract: Eye protection can be avoided.

Treatment of narrow-band UVB treatment considerations

For NB-UVB irradiation, patients need to cooperate with the treatment, wear protective eyepieces, and men protect the external genitalia. The range of skin exposed by each exposure should be consistent or shrinking.

In the case of whole body irradiation, if there is discomfort such as dizziness or palpitation, please inform the doctor promptly, or push the door out of the treatment room.

Tell the doctor the reaction after the exposure, so that the doctor can further adjust the dose according to the condition, and finally get satisfactory results.

Younger patients are best accompanied by family members.