311 narrow band UVB dermatology treatment instrument

Principle of treatment

At present, most hospitals use PUVA technology, which requires simultaneous irradiation of UVA ultraviolet light and oral photosensitive medical tablets. However, the side effects caused by UVA and the side effects caused by photosensitive medical tablets are obvious. The narrow-band UVB illuminator solves the problem of excessive UV exposure. Not only can patients fully accept the narrow-spectrum UVB emission of light with a wavelength range of 311-312 nm (this range is the most beneficial part of natural sunlight), while UVB treatment does not require taking other auxiliary medicines. The side effects of using photosensitive medicine in traditional PUVA methods are avoided, and these features make narrow-band UVB increasingly popular among patients and doctors.

Traditional broad-band UVB lamps emit light in the wavelength range of 280-330 nm, and clinical studies have shown that light below 300 nm can cause severe burns and increase the risk of skin cancer. Therefore, 311 narrow-band UVB emission of light in the 311-312 nm wavelength range is considered to be the safest and most efficient light.

Biological mechanism of action

1. Stimulate the proliferation and migration of melanocytes. When melanocytes absorb UVB energy, they can stimulate the activity of tyrosinase, accelerate the oxidation and polymerization of tyrosine, and increase the synthesis of melanin.

2.can promote keratinocytes release melanocyte proliferation and differentiation factors such as endothelin-1, fibroblast growth factor, etc.;

3.UVB has an immunosuppressive effect, which can prevent migration and proliferation of melanocytes from damage. NB-UVB irradiation treatment is divided into whole body irradiation and local irradiation, and the former or the latter depends on the type of the disease. At the same time, the irradiation process can be supplemented by other treatments, such as injection of Chinese and Western medicine preparations, oral, topical and epidermal transplantation.

Treatment advantage

The emergence of 311 nm narrow-band UVB has made it possible to improve the irradiation intensity and shorten the treatment time, which has greatly improved the therapeutic effect of various skin diseases. 311 narrow-band uvb is also a new method for the treatment of vitiligo. After phototherapy, the skin lesions in the patient can increase the tyrosinase activity in the skin, which promotes the synthesis of melanocytes, thereby achieving the purpose of cure. Clinical practice shows that the 311nm narrow band The efficacy of UVB is superior to traditional phototherapy. In clinical practice, we also found that before the application of 311 narrow-band UVB treatment, such as combined with traditional Chinese medicine fumigation treatment system or medicated bath therapy will achieve better therapeutic effect.

Superiority

Short course of treatment, fast effect, total effective rate of more than 90%; no need to take other auxiliary drugs, avoiding the side effects caused by the use of photosensitizing drugs; effective light output intensity, no phototoxic side effects, good safety and tolerance Sexuality has no significant effect on normal skin, avoiding the possibility of skin burns and carcinogenesis caused by traditional broad-band UVB.

treatment method

311 narrow-band UVB dermatological treatment instrument is better than broad-spectrum UVB, the incidence of erythema reaction is low, the disease is relieved for a long time, the effect is similar to PUVA, but it does not need to take medicine, the cost is low, it can be used for pregnant women and children, and the carcinogenicity is small. Wait. Irradiate once every other day, 15-20 times for a course of treatment. Clinical results in countries such as Europe and the United States indicate that the total effective rate is over 95%.