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BB-UVA vs. NB-UVB in the treatment of vitiligo: a randomized controlled clinical study (single blinded).

El-Mofty M1, Mostafa W, Youssef R, El-Fangary M, El-Ramly A, Mahgoub D, Fawzy M, El-Hawary M.

Author information

Abstract

BACKGROUND:

Vitiligo is an acquired pigmentary disorder that affects between 1% and 2% of the general population. Phototherapy remains the cornerstone of treatment, with NB-UVB being the most frequently used. BB-UVA can be a plausible alternative for darker population; skin photo type III and IV.

PATIENTS AND METHODS:

The study was a prospective, randomized, controlled, and single-blinded clinical trial, conducted on 40 patients with bilateral symmetrical vitiligo. The patients were randomly divided into two equal groups; group (A) received a fixed dose of 15 J/cm(2) BB-UVA, while group (B) received NB-UVB. The study was conducted for a period of 16 weeks (48 sessions).

RESULTS:

The final percentage of clinical improvement was significantly higher (P = 0.047) within the BB-UVA group (63.82% �� 27.42), than within the NB-UVB group (44.32% �� 29.78).

CONCLUSION:

BB-UVA can be considered as an alternative treatment line for vitiligo.

© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

KEYWORDS:

BB-UVA; NB-UVA; vitiligo

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