A comparison of the efficacy and relapse rates of narrowband UVB (TL-01) monotherapy vs. etretinate (re-TL-01) vs. etretinate-PUVA (re-PUVA) in the treatment of psoriasis patients.

Type:Uv phototherapy   Time:2017-11-22 10:08:08
A comparison of the efficacy and relapse rates of narrowband UVB (TL-01) monotherapy vs. etretinate (re-TL-01) vs. 
etretinate-PUVA (re-PUVA) in the treatment of psoriasis patients.
Forty-five patients with extensive chronic plaque or guttate psoriasis were treated with either narrowband (TL-01) 
phototherapy, etretinate TL-01 combination therapy (re-TL-01) or etretinate and PUVA (re-PUVA) (15 patients in each 
group). Re-PUVA was the most effective therapy with 100% satisfactory clearance rate. TL-01 monotherapy had an 80% 
success rate; the relapse rate compared favourably with re-PUVA (50% in remission after 6 months). In the 
etretinate-TL-01 group, there was a 93% success rate and a one-third reduction in the total irradiation dose (8.0 
J/cm2 vs. 12.7 J/cm2) but the relapse rate was higher, only 33% remaining in remission after 6 months.
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