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Narrow-band UVB (311 nm) versus conventional broad-band UVB with and without dithranol in phototherapy for psoriasis.

BACKGROUND:

A narrow-band UVB lamp (Philips TL 01) emitting a peak of approximately 311 nm was developed to improve the 

phototherapy for psoriasis. Only a few studies have been performed with promising results.

OBJECTIVE:

The therapeutic efficacy of the Philips TL 01 lamp in a new 100 W version was compared with conventional broad-band 

lamps (Sylvania UV 6) in a controlled trial.

METHODS:

Twenty-three patients with psoriasis were treated with half-body exposures from the different UVB sources. The rate of clearing was monitored by estimation of the Psoriasis Area and Severity Index. All patients used emollients; excessive scaling was removed with salicylic acid in yellow petrolatum. In 13 patients dithranol in a modified Ingram regimen was added. In most cases the study was discontinued once a difference between the two sides was evident.

RESULTS:

In 20 of 23 cases the TL 01 lamp proved to be significantly more effective than the conventional source. Application of dithranol provided a substantial additional therapeutic effect. With the high-intensity TL 01/100W bulbs, exposure times were comparable to broad-band UVB phototherapy.

CONCLUSION:

The therapeutic efficacy of Philips TL 01/100W and its practicability for psoriasis phototherapy have been 

demonstrated.

www.kerneluvb.com----The leader manufacturer of UVB Phototherapy.