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A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light eruption.
Type:Uv phototherapy Time:2017-11-17 11:44:37A comparison of narrow band phototherapy (TL-01) and photochemotherapy (PUVA) in the management of polymorphic light
eruption.
Bilsland D1, George SA, Gibbs NK, Aitchison T, Johnson BE, Ferguson J.
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Abstract
Twenty-five patients suffering from severe polymorphic light eruption (PLE) were randomized to either
photochemotherapy (PUVA) or narrow-band phototherapy (TL-01 UVB) treatment in early spring; patients receiving UVB
were given placebo tablets to achieve a matching therapy procedure. During the 4 months following treatment, patient
exposure to solar UVB was monitored with polysulphone badges. PLE occurrence, severity, and restriction of outdoor
activity were recorded, using weekly diary-sheets. Analysis of covariance on this data, using the logarithm of UVB
exposure as the explanatory variable, showed no significant differences between the treatments. TL-01 UVB is an
effective alternative to PUVA in the management of PLE.