Narrow-band UVB (TL-01) phototherapy: an effective preventative treatment for the photodermatoses.

Type:Uv phototherapy Time:2017-11-08 10:27:33

Twenty patients with photodermatoses [actinic prurigo (n = 6), hydroa vacciniforme (n = 4), idiopathic solar urticaria

(n = 1), amiodarone-induced photosensitivity (n = 1) and a range of cutaneous porphyrias (n = 8)] were treated with a

'hardening' course of narrow-band ultraviolet B (TL-01) phototherapy in springtime. The response to phototherapy was

monitored subjectively, by interviewing patients after the summer, and objectively by monochromator phototesting,

before and after phototherapy. Fifteen patients reported that treatment was worthwhile. Monochromator phototesting

after phototherapy revealed a fourfold increase in the minimal erythema dose in those with abnormal photosensitivity

to ultraviolet A wavebands. Adverse effects included erythema (seven patients), pruritus (five) and provocation of the

eruption (four). We now routinely consider narrow-band UVB phototherapy for problem photodermatoses.

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