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Calcipotriol/calcipotriene (Dovonex/Daivonex) in combination with phototherapy: a review.

Koo J1.

Author information

Abstract

BACKGROUND:

Calcipotriol/calcipotriene (Dovonex/Daivonex) ointment plus phototherapy has been used in the treatment of psoriasis.

OBJECTIVE:

We will attempt to clarify two issues: First, is there any benefit to combining the above treatment modalities? 

Second, is there any increased risk associated with the use of the combination?

METHODS:

A complete review of the literature revealed four studies dealing with the combination of calcipotriol with UVB 

phototherapy and three studies dealing with the combination of calcipotriol with PUVA phototherapy.

RESULTS:

These studies showed an advantage to the use of the combination compared with the use of either treatment alone.

CONCLUSION:

Topical calcipotriol enhances the effect of UVB and PUVA phototherapy.

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