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Acitretin in combination with UVB or PUVA.

Combination therapy of psoriasis with acitretin and phototherapy (psoralen-ultraviolet A [PUVA] or ultraviolet B 

[UVB]) offers multiple advantages over use of either modality alone. As monotherapy, acitretin in doses of 50 mg/day 

is moderately effective, but is associated with numerous side effects. Single modality treatment with UVB or PUVA 

involves multiple visits over a period of months and is also associated with dose-limiting side effects. When used in 

combination, lower doses of both modalities can be used more effectively, helping to reduce side effects. In addition, 

clearing occurs much more quickly, reducing treatment time and number of phototherapy visits. Moreover, patients whose 

psoriasis does not clear with monotherapy will often achieve significant clearing with the combination of acitretin 

and phototherapy.

www.kerneluvb.com----The leader manufacturer of UVB Phototherapy.