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Advances in psoriasis treatment.

Psoriasis is a complex disorder that negatively impacts quality of life. Treatment strategies must address both 

psychosocial and physical aspects of the disease. Psoriasis can be categorized into localized and generalized forms 

for treatment purposes. In either case, the treatment plan should include obtaining rapid control of the disease and 

maintaining that control. For localized disease, recent data support the combined use of topical corticosteroids with 

a noncorticosteroid agent (topical calcipotriene or tazarotene). For generalized disease, UVB phototherapy is an 

effective treatment that permits both rapid control and long-term maintenance. Use of low doses of acitretin (25mg qd 

or qod) potentiates both UVB and PUVA therapy. For patients unresponsive to phototherapy or who are not able to come 

on a regular basis, methotrexate is an effective alternative. Cyclosporine is useful, especially for short-term use in 

settings of acute exacerbation, but should be replaced by other modalities for long-term maintenance. Other agents 

that have a place in treatment of generalized psoriasis include hydroxyurea and mycophenolate mofetil.

www.kerneluvb.com----The leader manufacturer of UVB Phototherapy.