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Fujii N1, Uetsu N, Hamakawa M, Futamura S, Okamoto H, Horio T.

Author information

Abstract

A patient with psoriasis vulgaris had been successfully treated with PUVA and UVB therapy. During maintenance 

phototherapy, he suddenly became photosensitive and developed eczematous eruption. Minimal response doses to UVB and 

UVA were extremely low--1.09 mJ/cm2 and 0.3 J/cm2, respectively. No chemical substances were identified as the 

responsible photosensitizer. The condition was diagnosed as chronic actinic dermatitis (CAD). PUVA therapy was 

unsatisfactory because it was not possible to administer an adequate dose of UVA. Oral cyclosporine, topical 

corticosteroid and sunscreen were used with beneficial therapeutic effects on psoriasis and CAD. As far as we know, 

the development of CAD during phototherapy has not been previously reported.

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