Photo(chemo) therapy for vitiligo.

Type:Uv phototherapy Time:2017-09-18 10:49:24

Vitiligo has always been difficult to treat. Several modes of treatment are available, but the therapeutic effect

varies greatly, and rarely does one achieve complete repigmentation. One of the most efficient treatment methods is

photo(chemo) therapy. Already in ancient Egypt, vitiligo lesions were treated with extracts of the Ammi maius plant

followed by exposure to the sun. This principle is at the basis of the photochemotherapy or PUVA therapy, whereby UVA

irradiations are given 2 h after administration of 8-methoxypsoralen, a photosensitizer. Another efficient treatment

form is UVB phototherapy, particularly narrow-band UVB. This not only gives good therapeutic results but also has the

advantage of eliminating the need for a photosensitizer. All these treatments must be applied for many months to be

efficient. They can also be combined with various surgical skin-grafting techniques. A newer approach is targeted UVB

phototherapy, whereby xenon-chloride lasers or monochromatic excimer light is used.

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