Topical pseudocatalase mousse and narrowband UVB phototherapy is not effective for vitiligo: an open, single-centre study.

Type:Uv phototherapy   Time:2017-09-18 10:45:51
Topical pseudocatalase mousse and narrowband UVB phototherapy is not effective for vitiligo: an open, single-centre 
study.
We report an open single-centre trial to assess the efficacy of topical pseudocatalase mousse applied twice daily to 
the hands and face of vitiligo patients, in combination with twice-weekly suberythemogenic narrowband UVB 
phototherapy. The regime was generally safe and well tolerated, although several patients experienced mild transient 
skin rashes in association with application of the mousse and one patient suffered severe pruritus. The primary 
efficacy variable was the percentage change in area affected by vitiligo as assessed by digital interpretation of 
standardized photographs of the face and hands. There was no clear evidence of the efficacy of the regime and in fact 
a slight tendency overall to worsening of the patients' vitiligo.
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