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Narrowband UVB LAMP phototherapy in combination with other therapies for vitiligo: mechanisms and efficacies.
Type:Uv phototherapy Time:2016-12-29 10:14:47Narrowband ultraviolet B phototherapy in combination with other therapies for vitiligo: mechanisms and efficacies.
Yazdani Abyaneh M1, Griffith RD, Falto-Aizpurua L, Nouri K.
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Abstract
Vitiligo is a disorder of pigmentation affecting about 1% of the global population. It is a psychologically devastating
disease with suboptimal treatment options. Narrowband ultraviolet B (NB-UVB) phototherapy has become a first-line choice for
treating generalized disease. In recent years, topical calcineurin inhibitors, vitamin D analogues, antioxidant agents and
other therapies have been combined with NB-UVB to improve its efficacy. This article will address what is known about the
mechanisms of action of these treatments and how they may complement NB-UVB on a cellular level, as well as offer a
comprehensive, evidence-based review of clinical outcomes with combination therapies.
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