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Chanisada Tuchinda1, Holly A. Kerr1, Charles R. Taylor2, Heidi Jacobe3, Bettany M. Bergamo4, Craig Elmets4, Jennifer Rivard1 andHenry W. Lim1

Keywords:

phototherapy;UVA1

Background: The efficacy and safety of UVA1 (340�C400 nm) phototherapy were established by studies from European countries.

Purpose: Evaluate experience with UVA1 phototherapy for patients with cutaneous diseases in the United States.

Methods: A retrospective analysis of 92 cases of UVA1-treated cutaneous conditions from four medical centers in the United States was performed.

Results: Two-third of the patients showed a fair to good response (26�C100% improvement) and one-third of the patients showed a poor response (0�C25% improvement). Diseases with a moderate to good response (51�C100% improvement) included scleredema adultorum, hand or foot dermatitis, atopic dermatitis, morphea (medium or medium- to high-dose UVA1), systemic sclerosis, and urticaria pigmentosa. Besides tanning, other adverse effects were found in 15% of patients, which include pruritus, erythema, tenderness, and burning sensation. Patients with skin types I�CIII responded better that those with a darker skin type.

Conclusion: UVA1 phototherapy is a useful and well-tolerated treatment option for a variety of skin conditions.

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