Psoriasis Phototherapy
Type:Uv phototherapy Time:2016-09-08 9:16:02It has long been recognized that daily, short, non-burning exposure
to sunlight helped to clear or improve psoriasis in some patients.
Niels Finsen was the first physician to investigate the therapeutic
effects of sunlight scientifically and to use selected portions of the
solar spectrum in clinical practice. This became known as phototherapy.
Sunlight
contains many different wavelengths of light. It was during the early
part of the 20th century that it was recognised that for psoriasis the
therapeutic property of sunlight was due to the wavelengths classified
as ultraviolet (UV) light.
Ultraviolet
wavelengths are subdivided into UVA (380¨C315 nm) UVB (315¨C280 nm), and
UVC (< 280 nm). Ultraviolet B (UVB) (315¨C280 nm) is absorbed by the
epidermis and has a beneficial effect on psoriasis. There are two types
of UVB lamps: Narrowband UVB (311 to 312 nm), and Broadband (Wideband,
or "FS" type) UVB (290-320 nm). UVB Broadband is more erythemal and
therefore requires shorter exposure time, while UVB Narrowband does not
include the spectrum of less than 300 nanometers, allowing much higher
doses without erythema, and thus considered safer. The UVB Narrowband
lamp was developed by Philips Lighting specifically to match the action
spectrum of psoriasis, with a sharp emission peak at 311nm, to have
increased effectiveness compared to broadband lamps. Exposure to UVB
several times per week, over several weeks can help people attain a
remission from psoriasis. Sometimes it is needed to continue the
treatments once a week as maintenance, or the chronic disease will
return.
In hospitals, ultraviolet light
treatment is frequently combined with topical (coal tar, calcipotriol)
or systemic treatment (Retinoids) as there is a synergy in their
combination. The Ingram regime involves UVB and the application of
anthralin paste. The Goeckerman regime combines coal tar ointment with
UVB. Because coal tar includes unknown ingredients that might cause
cancer, and is a time intensive treatment, the use of coal tar has
fallen out of favor.
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