Psoriasis Phototherapy

Type:Uv phototherapy   Time:2016-09-08 9:16:02
It has long been recognized that daily, short, non-burning exposure to sunlight helped to clear or improve psoriasis in some patients. Niels Finsen was the first physician to investigate the therapeutic effects of sunlight scientifically and to use selected portions of the solar spectrum in clinical practice. This became known as phototherapy.

Sunlight contains many different wavelengths of light. It was during the early part of the 20th century that it was recognised that for psoriasis the therapeutic property of sunlight was due to the wavelengths classified as ultraviolet (UV) light.

Ultraviolet wavelengths are subdivided into UVA (380¨C315 nm) UVB (315¨C280 nm), and UVC (< 280 nm). Ultraviolet B (UVB) (315¨C280 nm) is absorbed by the epidermis and has a beneficial effect on psoriasis. There are two types of UVB lamps: Narrowband UVB (311 to 312 nm), and Broadband (Wideband, or "FS" type) UVB (290-320 nm). UVB Broadband is more erythemal and therefore requires shorter exposure time, while UVB Narrowband does not include the spectrum of less than 300 nanometers, allowing much higher doses without erythema, and thus considered safer. The UVB Narrowband lamp was developed by Philips Lighting specifically to match the action spectrum of psoriasis, with a sharp emission peak at 311nm, to have increased effectiveness compared to broadband lamps. Exposure to UVB several times per week, over several weeks can help people attain a remission from psoriasis. Sometimes it is needed to continue the treatments once a week as maintenance, or the chronic disease will return.

In hospitals, ultraviolet light treatment is frequently combined with topical (coal tar, calcipotriol) or systemic treatment (Retinoids) as there is a synergy in their combination. The Ingram regime involves UVB and the application of anthralin paste. The Goeckerman regime combines coal tar ointment with UVB. Because coal tar includes unknown ingredients that might cause cancer, and is a time intensive treatment, the use of coal tar has fallen out of favor.
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