Ultraviolet phototherapy of uremic pruritus

Type:Uv phototherapy   Time:2015-03-31 16:57:27
Ultraviolet phototherapy of uremic pruritus.
Gilchrest BA.
Abstract
Repeated exposure to mid-range ultraviolet light (UVB) can dramatically relieve the pruritus associated with 

uremia. The efficacy of UVB phototherapy in uremic pruritus has been established in a controlled trial; experience 

with 38 patients suggests that 80 to 90% of those receiving 6 to 8 exposures respond favorably within the treatment 

period (2 to 5 weeks). Treatment frequency appears not to influence the remission rate, although patients on more 

intensive schedules experience relief sooner than those treated once weekly. Remissions are long-lasting in many 

patients, sometimes longer than 2 years. Patients with recurrent pruritus respond to phototherapy at least as well 

as previously untreated patients and tend to improve more rapidly. UVB phototherapy appears to exert its beneficial 

effect systemically rather than locally, but its mechanism of action is otherwise unknown.
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