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  • 2015-04-13 16:08:48   The elevation of serum 25(OH)D and cathelicidin LL-37 could be an additional possible mechanism of action of NB-UVB therapy in the treatment of psoriasis.
    BACKGROUND:
    Narrowband ultraviolet B (NB-UVB) has been widely used in the treatment of psoriasis. It has been shown that vitamin D is a major regulator of the expression of human anti...
    VIEW
  • 2015-04-10 16:19:31   Low-dose NB-UVB treatment gives a significant increase (P < 0.001) of the vitamin D status in persons with low initial levels of 25(OH)D, but no effect on the folate level.
    BACKGROUND:
    A variety of studies have shown beneficial effects of different types of phototherapy in skin disorders. Such therapy leads to enhanced cutaneous vitamin D synthesis, whic...
    VIEW
  • 2015-04-10 16:18:58    It is critical for dermatologists to recognize the role of BB-UVB as a complement to NB-UVB phototherapy for patients who cannot tolerate or experience an inadequate therapeutic response from NB-UVB.
    Broadband ultraviolet B (BB-UVB) phototherapy has demonstrated efficacy in the treatment of cutaneous disorders including psoriasis, atopic dermatitis, uremic pruritus and idiopathic pruritus. In the ...
    VIEW
  • 2015-04-10 16:18:14   NB-UVB phototherapy represents a valid second-line treatment in paediatric patients affected by GVHD and refractory to immunosuppressive first-line treatment.
    BACKGROUND:

    Graft-versus-host disease (GVHD) represents an important complication following allogeneic bone marrow transplantation. In recent years, narrowband ultr...
    VIEW
  • 2015-04-10 16:17:34   UVB narrow-band as a safe and well tolerated alternative treatment for notalgia paresthetica.
    BACKGROUND:

    Notalgia paresthesica is a disorder of unknown origin characterized by pruritus localized to the patients' back. Local pain, burning or paresthesias hav...
    VIEW
  • 2015-04-10 16:17:09    phototherapy is a safe, effective and well-tolerated, first-line therapy in patients with early-stage cutaneous T-cell lymphoma, with prolonged disease-free remissions being achieved

    INTRODUCTION:
    Mycosis fungoides (MF) is a non-Hodgkin's T-cell lymphoma of the skin that often begins as limited patches and plaques with slow progression to system...
    VIEW
  • 2015-04-10 16:16:25   Combination of methotrexate and NBUVB phototherapy provides more rapid clinical improvement compared with NBUVB monotherapy in the treatment for chronic plaque-type psoriasis.
    BACKGROUND:
    Psoriasis is a chronic, recurring inflammatory disease affecting the skin, joints and nails that has a significant negative impact on the quality of life. Efficacy of comb...
    VIEW
  • 2015-04-10 16:14:40   UVB Phototherapy successfully uses the short-term effects of ultraviolet light against inflammation and proliferatio
    Phototherapy successfully uses the short-term effects of ultraviolet light against inflammation and proliferation. For its long-term effects, however, ultraviolet light was recently classified as a ca...
    VIEW
  • 2015-04-10 16:13:53   Local UVB radiation of the skin influences systemic immune reactions and attenuates systemic autoimmunity via the induction of skin-derived tolerogenic DCs and Tregs
    OBJECTIVE:
    Environmental conditions (eg, latitude) play a critical role in the susceptibility and severity of many autoimmune disorders, including multiple sclerosis (MS). Here, we in...
    VIEW
  • 2015-04-10 16:12:37   GF¦Â1/Smad signalling is altered in a psoriatic model and may play a role in the mode of action of salt water soaks and NB-UVB phototherapy of psoriasis.
    The role of transforming growth factor-¦Â1 (TGF¦Â1) and Smad signalling has not been established in psoriasis treatment. We aimed to investigate the effect of combined treatment with salt water soaks an...
    VIEW


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