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  • 2015-04-21 16:08:09   The combinations of aromatic retinoid with (selective) UVB irradiation (ReSUP) or with PUVA therapy (RePUVA) are highly effective
    The combination of different antipsoriatics or treatment regimens should increase the therapeutic effect and reduce the adverse reactions. The combination of dithranol and tar (cignolin-salicyl-vaseli...
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  • 2015-04-21 16:06:57   UVA induces ANA in mice, and PUVA-induced ANA may be due to the UVA component of this therapy.
    PUVA therapy has been reported to induce antinuclear antibodies (ANA). The generation of ANA following ultraviolet irradiation was studied experimentally in albino mice. When treated with long wave ul...
    VIEW
  • 2015-04-20 15:41:56    UV-therapy might be worth trying in many patients with chronic urticaria.
    Fifteen patients with chronic urticaria were treated with ultraviolet light B (UVB) for 1-3 months during the spring 1984 and a follow-up study was performed in November 1984-January 1985. Patien...
    VIEW
  • 2015-04-20 15:41:13   both UVB and PUVA treatments suppress the induction of contact hypersensitivity by a mechanism that involves suppressor lymphocytes.
    Skin cancers induced in mice by UVB, i.e., 280-320 nm radiation, are highly antigenic. They grow progressively in UVB-irradiated hosts because of certain specific immunologic alterations that are indu...
    VIEW
  • 2015-04-20 15:40:06   combined treatment with UVB and 8-MOP plus UVA may have a greater effect than either treatment alone.
    Photochemotherapy with oral 8-methoxypsoralen (8-MOP) plus long wavelength UV radiation (UVA) has been shown to affect lymphoid cells circulating through the skin. An in vitro assay was developed to m...
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  • 2015-04-20 15:39:24    changes in the epidermis and dermis, with damage to keratinocytes and an inflammatory infiltrate in the dermis, both of which occur later and are of longer duration than the damage induced by UVA, UVB, or UVC alone
    Psoralen phototoxicity has several features which distinguish it from other cutaneous responses to UV radiation, with or without an exogenous photosensitizing agent. Erythema resulting from psoralen p...
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  • 2015-04-20 15:38:34   In doses sufficient to induce coal tar phototoxicity manifested by the smarting reaction, UVA does not add to the known benefits of UVB phototherapy.
    Multiple studies have demonstrated that the doses of ultraviolet A (UVA) (320-400 nm) achieved with ultraviolet sources presently used for phototherapy for psoriasis are inadequate to induce coal...
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  • 2015-04-20 15:37:22   PUVA treatments of longer duration are preferably performed in a lying position
    UV irradiation devices for the treatment of psoriasis. Desirable spectra and various criteria for selection].
    Special fluorescent lamps as well as filtered high pressure lamps are use...
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  • 2015-04-20 15:36:00   UVB and PUVA do not lead to harmful concentrations of vitamin D metabolites in the blood of healthy subjects.
    The serum concentrations of the major vitamin D metabolites (25-hydroxyvitamin D(2 + 3) (25-OH-D), 1,25-dihydroxyvitamin D(2 + 3) (1,25-(OH)2-D), and 24,25-dihydroxyvitamin D(2 + 3) (24,25-(OH)2-D) we...
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  • 2015-04-20 15:35:24   PUVA treatment perturbs the composition or organization of epidermal cell surface glycoconjugates to induce alterations in lectin stainings.
    The alterations in lectin fluorescence stainings to the epidermis were examined in guinea pig skin treated with topical application of a 1% 8-methoxypsoralen (8-MOP) solution plus long-wave ultraviole...
    VIEW


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